Computed tomographic colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysis
Background In addition to detecting colorectal neoplasia, abdominal computed tomography
(CT) with colonography technique (CTC) can also detect unsuspected extracolonic cancers
and abdominal aortic aneurysms (AAA). The efficacy and cost-effectiveness of this combined
abdominal CT screening strategy are unknown. Methods A computerized Markov model was
constructed to simulate the occurrence of colorectal neoplasia, extracolonic malignant
neoplasm, and AAA in a hypothetical cohort of 100 000 subjects from the United States who …
(CT) with colonography technique (CTC) can also detect unsuspected extracolonic cancers
and abdominal aortic aneurysms (AAA). The efficacy and cost-effectiveness of this combined
abdominal CT screening strategy are unknown. Methods A computerized Markov model was
constructed to simulate the occurrence of colorectal neoplasia, extracolonic malignant
neoplasm, and AAA in a hypothetical cohort of 100 000 subjects from the United States who …
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